Scientific Advisory Committee
Douglas E. Brash, PhD
Douglas E. Brash, PhD, is Professor of Therapeutic Radiology, Genetics, and Dermatology at Yale School of Medicine. After receiving degrees in engineering physics and biophysics, and postdoctoral training at Harvard Medical School, he joined the National Cancer Institute to begin his studies of sunlight's role in causing skin cancer. At Yale, his research group discovered that the p53 and PTCH tumor suppressor genes are mutated by sunlight, that p53 is required for programmed cell death in response to ultraviolet light, and that sunlight drives mutant cells in normal skin to form clones.
